JNK3 (MAPK10)

分子式：

分子量：

别名：
MAPK10 antibody, FLJ12099 antibody, FLJ33785 antibody, JNK3 antibody, JNK3A antibody, MGC50974 antibody, PRKM10 antibody, p493F12 antibody, p54bSAPK antibody, Mitogen-activated protein kinase 10 antibody, MAP kinase p49 3F12 antibody, Stress-activated pro

产品订购：

品名	规格	包装	单价	货期
JNK3 (MAPK10)		100ul	询价	现货

性状：
【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5493(2)
【用途】WB , ICC , FC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】54kDa

质量标准：
【产品介绍】JNK3 is a member of the MAP kinase family.
MAP kinases act as an integration point for
multiple biochemical signals, and are involved in a
wide variety of cellular processes such as
proliferation, differentiation, transcription regulation
and development. This protein is a neuronal-specific form
of c-Jun N-terminal kinases (JNKs). Through
its phosphorylation and nuclear localization, this
kinase plays regulatory roles in the signaling
pathways during neuronal apoptosis. Beta-arrestin 2,
a receptor-regulated MAP kinase scaffold protein, is
found to interact with, and stimulate the phosphorylation
of this kinase by MAP kinase kinase 4 (MKK4).
Cyclin-dependent kianse 5 can phosphorylate, and inhibit
the activity of this kinase, which may be important
in preventing neuronal apoptosis (1).

Recommended Applications
WB, ICC, FC
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
ICC: 1:100 - 250
FC: 1:10 - 100
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) HeLa, (B) 293T,
(C) SH-SY5Y, and (D) human heart lysates using
anti-JNK3 RabMAb (cat. #5474-1).

Immunofluorescent staining of 293 cells using
anti-JNK3 RabMAb (cat. #5474-1).

Specificity
A synthetic peptide corresponding to residues near
the C-terminus of human JNK3 was used as an immunogen.

贮存：
Store at -20° C. Buffer: PBS (pH 7.2), 0.01% sodium
azide, 50% Glycerol and 0.05% BSA. Stable for 12 months
from date of receipt.