Fumitremorgin C
MDL：
MFCD08702652
Molecular Formula：
C22H25N3O3
Molecular Weight：
379.45
Alias：
Tryptoquivaline
FTC
Product order：
| Name |
Specifications |
Packing |
Price |
Delivery |
| Fumitremorgin C |
98% |
0.25mg |
RMB 2160.4 |
Consulting service |
Character：
Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
Storage：
储存温度:−20°C
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